Topkapi Palace is located in the old city center. the best way to reach it is on foot taken into consideration that there are a lot of attractions in one place that you should not miss. the tram line that will take you here is T1. Tram stop where you should get off is called: Gülhane istasyonu. from this tram stop you should walk additional 500 meters in order to reach the Topkapi Palace.